Paper-3 content

Paediatric  Paper-3:

Format of examination:

Total number of questions: 50

MCQ-25

SAB – 25 

PATHOLOGY —GENERAL PATHOLOGY, IMMUNOLOGY, GENETICS AND MOLECULAR BIOLOGY, HISTOPATHOLOGY AND SYSTEMIC PATHOLOGY

MICROBIOLOGY-BACTERIOLOGY, VIROLOGY, PARASITOLOGY AND MYCOLOGY

A. PATHOLOGY

General pathology: The following conception are to be correlated with different clinical entity cellular injury and death, inflammation and repair, granulomatous disorder, neoplasm, thrombosis, embolism, oedema.

Principles of commonly used cytological and histopathological investigations, factors affecting the quality of specimen and reporting scope and limitations of such investigations.

Immunology: basic principles, concept of host-agent-environment, mechanisms of immunity and auto-immunity, immune mediated diseases including graft versus host and tumor immunity, pathological basis of different investigative tools available based on immunological principles.

Genetics and molecular biology : basic concept, molecular basis of diseases, genetical basis of diseases, investigative tools available for these, their uses and limitations, pedigree analysis, genetic counseling principles. Histopathology

• Site of lesion including the microstructure
• General pathological description of the type of lesion
• Functional derangement following the lesion
• Micro-structural and chemical changes of the lesion

Systemic pathology: A student will be expected to know the following of the individual pathological situations in different diseases.

Respiratory system : Pneumonia, bronchiolitis, tonsillitis, bronchial asthma, lung abscess, bronchiectasis, pleural effusion, atelectasis.

Hematology and Oncology: Anaemia (nutritional, hemolytic, hemorrhagic and others), bleeding disorder (ITP, hemophilia, Von-Willebrands disease), Hodgkins and non-Hodgkins Lymphoma, leukemia, Wilms tumor, retinoblastoma, neuroblastoma and other childhood malignancy. Cardiovascular system: Rheumatic heart diseases, congenital heart diseases, infective endocarditis.

Central nervous system: Meningitis, encephalitis, GB syndrome, and hydrocephalous.

Gastrointestinal system:Hirschsprung diseases, congenital hypertrophic pyloric stenosis, appendicitis, hepatitis - acute & chronic, cirrhosis of liver, portal hypertension.

Nutritional disorder: PEM, macro and micro nutrient deficiency syndromes, iodine deficiency disorder, rickets, scurvy, xerophthalmia.

Genito-urinary system : Urinary tract infection, acute glomerulonephritis, nephrotic syndrome, acute renal failure, chronic renal failure.

Collagen disorder: Acute rheumatic fever, JIA, SI E

Neonatology: Low birth weight, respiratory distress syndrome, TORCH infection, neonatal jaundice, birth asphyxia, hemorrhagic discase of newborn.

Inborn error of metabolism, Phenylkctonuria, Galactossacmia Genetic and chromosomal disorders

Endocrinology: Thyroid - hypo and hyper function, pituitary anterior and posterior - hypo and hyper function, Pancreas - diabetes, adrenal gland - adrenal hyperplasia, pheochromocytoma.

• Recommended books: Relevant section in Robbins&Cotran Pathologic Basis of Diseases, Jawetz, Melnick and Adelberg’s Medical Microbiology and Nelson Textbook of Pediatrics and Forfar&Arneil's Textbook of Pediatrics.

B. MICROBIOLOGY

Bacteriology:

Basic bacteriology: Classification of microbial agents, normal microbial flora in human body, infection, sepsis, septicemia, bacteremia, spread of infection, control of infection. Bacterial culture, principles of bacterial growth, culture media, principles of serological techniques used in bacteriology, scope and limitation of bacteriological studies, collection and preservation of samples. 0 Pathogenesis and laboratory diagnosis of typical/atypical mycobacteria, diphtheria, pertussis, tetanus, pneumonia, enteric fever, meningitis, tetanus, gangrene, gonorrhea, dengue, syphilis including TORCH infection, staphylococcal and streptococcal infection, secretary and invasive enterocolitis Infection and immunosuppression.

• Recommended books: Relevant section in Nelson Textbook of Pediatrics and Forfar&Arneil’s Textbook of Pediatrics.andJawetz, Melnick and Adelberg’s Medical Microbiology

Virology:

Basic virology: viral structure, classification, replication, mode of transmission, pathogenesis and diagnosis of viral infection.

• Pathogenesis and diagnosis of diseases cause adenoviruses, Herpes virus, Hepatitis virus, Rotavirus, Rabies virus, Slow virus, Reovirus, Arbovirus, HIV, Measles and rubella, mumps, poliomyelitis
• Viral infection in congenital or acquired immuno-compromised child

Recommended books: Relevant section in Nelson Textbook of Pediatrics and Forfar&Arneil’s Textbook of Pediatrics.andJawetz, Melnick and Adelberg’s Medical Microbiology

Parasitology:

•  General parasitology: classification of parasites, transmission, infestation, body response to infestation, pathological basis of different laboratory diagnosis.
•  General features of rhizopodes, flagellates, nematodes, cestodes and trematodes.
•  Life cycle of parasites, pathogenesis and diagnosis of diseases caused bymalaria, leishmaniasis, toxoplasmosis, pneumocystosis, ascariasis, ankylostomiasis,strongyloidiasis, enterobiasis, filariasis, taeniasis, echinococcosis, sarcoptesscabii.

Recommended books: Relevant section in Parasitology by K.D.Chatterjee and Nelson Textbook of Pediatrics and Forfar&Arneil’s Textbook of Pediatrics.

Mycology:

•  General mycology : properties of fungus, classification of fungi, laboratory diagnosis

of fungal diseases.  

• Pathogenesis, clinical consequences and laboratory diagnosis of superficial and

cutaneous mycosis, deep mycosis

Recommended books: Relevant section Forfar&Arneil’s Textbook of Pediatrics.

in Nelson Textbook of Pediatrics and