Paper-3 content

General Pathology:

• Cellular injury and adaptation
• Disorders of growth, differentiation and morphogenesis
• Inflammation, necrosis, gangrene
• Wounds, ulcer, repair and healing process
• Tissue death and apoptosis
• Hyperplasia, Atrophy, Metaplasia, Dysplasia
• immune response, immunodeficiency, Vaccination, immunosuppression, Organ transplantation and mechanisms of rejection
• Thrombosis, Embolism, Acute and Chronic ischemia .
• Hematological disorders encountered in surgical practice ,hemophilia,thromboeytopenia,DIC

Neoplasia and Metastasis.

• Pathology of neoplasia, Classification of tumours, Tumour development and growth including metastasis, Principles of staging and grading of cancers, Principles of cancer therapy including surgery, radiotherapy, chemotherapy, immunotherapy and hormone therapy, Principles of cancer registration,Principles of cancer screening

General pathological principles including:

• The pathology of specific organ systems relevant to surgical care including cardiovascular pathology, respiratory pathology, gastrointestinal pathology, genitourinary disease, breast, exocrine and endocrine pathology, central and peripheral, neurological systems, skin, lymphoreticular and musculoskeletal systems

Microbiology

1. Bacteriology

1.1 Structure of a bacteria, Bacterial growth

1.2. Normal flora

1.3 Pathogenesis of bacterial lesions

1.4 Laboratory diagnosis of bacterial lesions

1.5 Microbial resistance

1.6 Bacteria causing common surgical lesions

1.7 Disinfection and sterilization

1.8 Hospital infection

2. Virology

2.1 Structure, replication and transmission of virus

2.2 Pathogenesis of viral] lesions

2.3 Laboratory diagnosis of viral infection

2.4 Surgically important virus

3. Parasitology

• Ascariasis, Hydatid cyst, Amoebiasis, Bilherziasis, Filariasis

4. Mycology

• Actinomycosis, Opportunostic fungal infection, Deep mycosis

5. Immunology

• Immunity and immunological response, Cellular and Humoral immunity
• Vaccination,
• Laboratory diagnosis of immunological disorders and immunological tests of different organs and system
• Autoimmunity
• Immunodeficiency disorders
• Major Histocompetability Complex, Tissue typing, Organ transplantation

6.Applied Microbiology

• Surgically important microorganisms including blood borne viruses
• Soft tissue infections including cellulitis, abscesses, necrotizing fasciitis, gangrene
• Sources of infection, Asepsis and antisepsis , Hospital acquired infections
• Sepsis and septic shock
• Principles of disinfection and sterilization
• Antibiotics including prophylaxis and resistance
• Principles of management of high risk patients