Idiopathic Thrombocytopenic Purpura(ITP)

Clinical Features:

• 1)Easy or excessive bruising.
• 2)Superficial bleeding into the skin that appears as pinpoint-sized reddish-purple spots (petechiae) that look like a rash, usually on the lower legs.
• 3)Bleeding from the gums or nose.
• 4)Blood in urine or stools.
• 5)Unusually heavy menstrual flow.

O/E: 

• Multiple petechiae & purpura over whole body with color Change. 
  

Investigations: 

• 1)CBC with PBF : thrombocytopenia
  
• 2) Urine R/M/E: exclude HSP
• 3)PT
• 4)APTT 
• 5) ANA - vasculitis 

Rx: 

1.Tab.cortan(prednisolone) 20 mg 

• 3+0+0.........1 months
• 2.5 +0+0......15 days
• 2+০+০..........15 days
• 1+০+০...........15 days 
• ১/২ +০+০.......15 days

Then

Tab.cortan(prednisolone) 5 mg 

• 1+0+0.......১৫ দিন 

Then,

Every alternative day Tab.Cortan(5mg) ......15 days

(১ টি tab.cortan 5 mg একদিন পর পর....১৫ দিন )

2.Cap.Sergel (20mg) 

• 1+0+1.......3 months( খাবারের আগে যতদিন cortan চলবে) 

3.Tab.Rocal-D 

• 1+0+1..........4 months

[Note : আমরা cortan এর পরিবর্তনে other drug use করতে পারি 

4.Tab.Eltrom(eltrombopag) 50mg

• 1+0+0.....3 months 

🎴Other options splenectomy.