Von Willebrand Disease

Clinical Features:

• 1)Excessive bleeding from an injury or after surgery or dental work.
• 2)Frequent nosebleeds that don't stop within 10 minutes.
• 3)Heavy or long menstrual bleeding.
• 4)Heavy bleeding during labor and delivery.
• 5)Blood in your urine or stool.
• 6)Easy bruising or lumpy bruises.

Investigations: 

• 1)CBC with PBF
  
• 2) PT - normal 
  
• 3) BT- Prolonged 
• 4) APTT- Prolonged 

Rx: (Hospital treatment) 

• Counselling about the disease 

1.inj.FVIII 100 unit 

• I/v stat & daily for 7 days 

OR 

inj.FFP 

• 1 unit I/v stat &daily..... 5-7 days 

if several bleeding 

inj.Traxyl 

• 1 amp i/v &tds.... 5-7 days 

if any infection 

inj. Ceftriaxone (1 gm) 

• 1vial i/v stat & bd..... 7 days 

Advice : pt Referred to hemato-oncologist for better management.