89. Pemphigus Vulgaris
Protocols
Clinical Features:
👉 Bullous skin disorder of poor prognosis.
👉 First lesion may occur in any part of the body.
👉 There is an offensive, characteristic odour.
👉 Later on eruptions may become generalised alongwith itching, loss of weight and anaemia.
👉 Bullae arise from a normal skin with erythema
around.
👉 Bullae tends to be tense due to contained serum.
👉 Rupture of bullae leaves a raw, exuding surface whichbecomes crusted.
👉 When crusts are shed, pigmentation remains formany weeks/months.
Treatment:
🗒️Rx:
👉 Hospitalise the patient.
👉 High calorie, high protein diet.
👉 1% aqueous Gentian violet is soothing and reducesbacterial infection or dress with Sofratulle andNeosporin ointment.
1.Cap.Moxin([post id="402" title="Amoxicillin"]) (500mgl
1+1+1+1......7 days
OR
Cap.Doxicap([post id="590" title="Doxycycline"]) (100mg)
1+0+1........10 days
2.Tab.Cortan(prednisone)(20mg)([post id="479" title="Prednisolone"])
1+0+1.........15 days then
1/2+0+1/2..........7 days then
1;2+0+0...…........7 days
3.Betaderm N cream(([post id="708" title="Betamethasone+Neomycin"])
দিনে ২ বার........... ১৫ দিন।
4.Betason N E/D ([post id="708" title="Betamethasone+Neomycin"])
২চোখে দিনে ৪ বার........ ৭ দিন
5.Tab.Ceevit DS (500mg)([post id="466" title="Ascorbic-Acid"])
1+0+0.............20 days
6.Tab.Endoxan([post id="709" title="Cyclophosphamide"])(50mg)
0+0+1...........1 month
7.Cap.Sergel(Esomeprazol) (20mg)([post id="392" title="Esomeprazole"])
1+0+1...........1 month(30 min before meal)